4E83
Crystal structure of human alpha-defensin 5, HD5 (Leu29NLe mutant)
Summary for 4E83
| Entry DOI | 10.2210/pdb4e83/pdb |
| Related | 1ZMP 4E82 4E86 |
| Descriptor | Defensin-5, CHLORIDE ION (3 entities in total) |
| Functional Keywords | beta-sheet structure, antimicrobial peptide, leu29nle mutant, paneth cells, antimicrobial protein |
| Biological source | Homo sapiens (human) |
| Cellular location | Secreted: Q01523 |
| Total number of polymer chains | 2 |
| Total formula weight | 7223.91 |
| Authors | Pazgier, M. (deposition date: 2012-03-19, release date: 2012-05-16, Last modification date: 2023-12-06) |
| Primary citation | Rajabi, M.,Ericksen, B.,Wu, X.,de Leeuw, E.,Zhao, L.,Pazgier, M.,Lu, W. Functional determinants of human enteric {alpha}-defensin HD5: crucial role for hydrophobicity at dimer interface. J.Biol.Chem., 287:21615-21627, 2012 Cited by PubMed: 22573326DOI: 10.1074/jbc.M112.367995 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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