4BL2
Crystal structure of PBP2a clinical mutant E150K from MRSA
Summary for 4BL2
| Entry DOI | 10.2210/pdb4bl2/pdb |
| Related | 4BL3 |
| Descriptor | PENICILLIN BINDING PROTEIN 2 PRIME, CADMIUM ION, CHLORIDE ION, ... (4 entities in total) |
| Functional Keywords | hydrolase, penicillin binding proteins, b-lactum antibiotics |
| Biological source | STAPHYLOCOCCUS AUREUS |
| Total number of polymer chains | 2 |
| Total formula weight | 147760.50 |
| Authors | Otero, L.H.,Rojas-Altuve, A.,Hermoso, J.A. (deposition date: 2013-04-30, release date: 2014-05-21, Last modification date: 2023-12-20) |
| Primary citation | Fishovitz, J.,Rojas-Altuve, A.,Otero, L.H.,Dawley, M.,Carrasco-Lopez, C.,Chang, M.,Hermoso, J.A.,Mobashery, S. Disruption of Allosteric Response as an Unprecedented Mechanism of Resistance to Antibiotics. J.Am.Chem.Soc., 136:9814-, 2014 Cited by PubMed: 24955778DOI: 10.1021/JA5030657 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.72 Å) |
Structure validation
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