4BIE
Crystal Structures of Ask1-inhibitor Complexes
Summary for 4BIE
Entry DOI | 10.2210/pdb4bie/pdb |
Related | 4BF2 4BHN 4BIB 4BIC 4BID |
Descriptor | MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5, GLYCEROL, N-(2-aminoethyl)-5-{2-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl}thiophene-2-sulfonamide, ... (4 entities in total) |
Functional Keywords | transferase, structure based desgin |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Cytoplasm: Q99683 |
Total number of polymer chains | 2 |
Total formula weight | 71933.85 |
Authors | Singh, O.,Shillings, A.,Craggs, P.,Wall, I.,Rowland, P.,Skarzynski, T.,Hobbs, C.I.,Hardwick, P.,Tanner, R.,Blunt, M.,Witty, D.R.,Smith, K.J. (deposition date: 2013-04-10, release date: 2013-07-03, Last modification date: 2023-12-20) |
Primary citation | Singh, O.,Shillings, A.,Craggs, P.,Wall, I.,Rowland, P.,Skarzynski, T.,Hobbs, C.I.,Hardwick, P.,Tanner, R.,Blunt, M.,Witty, D.R.,Smith, K.J. Crystal Structures of Ask1-Inhibtor Complexes Provide a Platform for Structure Based Drug Design. Protein Sci., 22:1071-, 2013 Cited by PubMed: 23776076DOI: 10.1002/PRO.2298 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.36 Å) |
Structure validation
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