4AY6

Human O-GlcNAc transferase (OGT) in complex with UDP-5SGlcNAc and substrate peptide

Summary for 4AY6

Entry DOI	10.2210/pdb4ay6/pdb
Related	1W3B 2J4O 2YDS 2YIY 4AY5
Descriptor	UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANS FERASE 110 KDA SUBUNIT, TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN 1, SULFATE ION, ... (4 entities in total)
Functional Keywords	transferase, glycosyl transferase
Biological source	HOMO SAPIENS (HUMAN) More
Cellular location	Isoform 2: Mitochondrion. Isoform 3: Cytoplasm. Isoform 4: Cytoplasm: O15294
Total number of polymer chains	8
Total formula weight	332013.57
Authors	Schimpl, M.,Zheng, X.,Blair, D.E.,Schuettelkopf, A.W.,Navratilova, I.,Aristotelous, T.,Ferenbach, A.T.,Macnaughtan, M.A.,Borodkin, V.S.,van Aalten, D.M.F. (deposition date: 2012-06-18, release date: 2012-10-24, Last modification date: 2012-12-12)
Primary citation	Schimpl, M.,Zheng, X.,Borodkin, V.S.,Blair, D.E.,Ferenbach, A.T.,Schuettelkopf, A.W.,Navratilova, I.,Aristotelous, T.,Albarbarawi, O.,Robinson, D.A.,Macnaughtan, M.A.,Van Aalten, D.M.F. O-Glcnac Transferase Invokes Nucleotide Sugar Pyrophosphate Participation in Catalysis Nat.Chem.Biol., 8:969-, 2012 Cited by PubMed: 23103942 DOI: 10.1038/NCHEMBIO.1108 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.3 Å)

Structure validation