4AXD

Inositol 1,3,4,5,6-pentakisphosphate 2-kinase in complex with AMPPNP

Summary for 4AXD

Entry DOI	10.2210/pdb4axd/pdb
Related	2XAL 2XAM 2XAN 2XAO 2XAR 4AQK 4AXC 4AXE 4AXF
Descriptor	INOSITOL-PENTAKISPHOSPHATE 2-KINASE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ZINC ION, ... (6 entities in total)
Functional Keywords	transferase, inositol kinase, phytic acid, protein kinase, inositide signalling
Biological source	ARABIDOPSIS THALIANA (THALE CRESS)
Total number of polymer chains	1
Total formula weight	52450.12
Authors	I Banos-Sanz, J.,Sanz-Aparicio, J.,Gonzalez, B. (deposition date: 2012-06-12, release date: 2012-07-04, Last modification date: 2023-12-20)
Primary citation	Banos-Sanz, J.I.,Sanz-Aparicio, J.,Whitfield, H.,Hamilton, C.,Brearley, C.A.,Gonzalez, B. Conformational Changes Undergone by Inositol 1,3,4,5,6-Pentakisphosphate 2-Kinase Upon Substrate Binding: The Role of N-Lobe and Enantiomeric Substrate Preference J.Biol.Chem., 287:29237-, 2012 Cited by PubMed: 22745128 DOI: 10.1074/JBC.M112.363671 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation