3W2T
Crystal structure of human depiptidyl peptidase IV (DPP-4) in complex with vildagliptin
3W2T の概要
エントリーDOI | 10.2210/pdb3w2t/pdb |
分子名称 | Dipeptidyl peptidase 4, beta-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
機能のキーワード | alpha/beta, beta-propeller, hydrolase, aminopeptidase, serine protease, secreted, signal-anchor, transmembrane, diabetes, glycoprotein, cell membrane, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
由来する生物種 | Homo sapiens (human) |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 176942.22 |
構造登録者 | Kishida, H.,Nabeno, M.,Miyaguchi, I.,Tanaka, Y.,Katou, R.,Akahoshi, F. (登録日: 2012-12-04, 公開日: 2013-05-15, 最終更新日: 2023-11-08) |
主引用文献 | Nabeno, M.,Akahoshi, F.,Kishida, H.,Miyaguchi, I.,Tanaka, Y.,Ishii, S.,Kadowaki, T. A comparative study of the binding modes of recently launched dipeptidyl peptidase IV inhibitors in the active site Biochem.Biophys.Res.Commun., 434:191-196, 2013 Cited by PubMed: 23501107DOI: 10.1016/j.bbrc.2013.03.010 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.36 Å) |
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