3VZB
Crystal structure of Sphingosine Kinase 1
Summary for 3VZB
Entry DOI | 10.2210/pdb3vzb/pdb |
Related | 3VZC 3VZD |
Descriptor | Sphingosine kinase 1, (2S,3R,4E)-2-aminooctadec-4-ene-1,3-diol, SULFATE ION, ... (5 entities in total) |
Functional Keywords | lipid kinase, transferase-inhibitor complex, transferase/inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: Q9NYA1 |
Total number of polymer chains | 3 |
Total formula weight | 121399.46 |
Authors | Min, X.,Walker, N.P.,Wang, Z. (deposition date: 2012-10-10, release date: 2013-05-08, Last modification date: 2024-05-29) |
Primary citation | Wang, Z.,Min, X.,Xiao, S.H.,Johnstone, S.,Romanow, W.,Meininger, D.,Xu, H.,Liu, J.,Dai, J.,An, S.,Thibault, S.,Walker, N. Molecular basis of sphingosine kinase 1 substrate recognition and catalysis. Structure, 21:798-809, 2013 Cited by PubMed: 23602659DOI: 10.1016/j.str.2013.02.025 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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