3UUC
Crystal structure of hERa-LBD (wt) in complex with bisphenol-C
Summary for 3UUC
Entry DOI | 10.2210/pdb3uuc/pdb |
Related | 3UU7 3UUA 3UUD |
Descriptor | Estrogen receptor, 4,4'-(2,2-dichloroethene-1,1-diyl)diphenol (3 entities in total) |
Functional Keywords | ligand-binding domain of nuclear hormone receptor, hormone receptor |
Biological source | Homo sapiens (human) |
Cellular location | Isoform 1: Nucleus. Isoform 3: Nucleus. Nucleus: P03372 |
Total number of polymer chains | 4 |
Total formula weight | 115991.90 |
Authors | Delfosse, V.,Grimaldi, M.,Bourguet, W. (deposition date: 2011-11-28, release date: 2012-08-22, Last modification date: 2023-12-06) |
Primary citation | Delfosse, V.,Grimaldi, M.,Pons, J.L.,Boulahtouf, A.,le Maire, A.,Cavailles, V.,Labesse, G.,Bourguet, W.,Balaguer, P. Structural and mechanistic insights into bisphenols action provide guidelines for risk assessment and discovery of bisphenol A substitutes. Proc.Natl.Acad.Sci.USA, 109:14930-14935, 2012 Cited by PubMed: 22927406DOI: 10.1073/pnas.1203574109 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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