3UUD

Crystal structure of hERa-LBD (Y537S) in complex with estradiol

Summary for 3UUD

Entry DOI	10.2210/pdb3uud/pdb
Related	3UU7 3UUA 3UUC
Descriptor	Estrogen receptor, Nuclear receptor coactivator 1, ESTRADIOL, ... (7 entities in total)
Functional Keywords	ligand-binding domain of nuclear hormone receptor, hormone receptor
Biological source	Homo sapiens (human) More
Cellular location	Isoform 1: Nucleus. Isoform 3: Nucleus. Nucleus: P03372 P03372 Nucleus (By similarity): Q15788
Total number of polymer chains	4
Total formula weight	61380.36
Authors	Delfosse, V.,Grimaldi, M.,Bourguet, W. (deposition date: 2011-11-28, release date: 2012-08-22, Last modification date: 2023-12-06)
Primary citation	Delfosse, V.,Grimaldi, M.,Pons, J.L.,Boulahtouf, A.,le Maire, A.,Cavailles, V.,Labesse, G.,Bourguet, W.,Balaguer, P. Structural and mechanistic insights into bisphenols action provide guidelines for risk assessment and discovery of bisphenol A substitutes. Proc.Natl.Acad.Sci.USA, 109:14930-14935, 2012 Cited by PubMed: 22927406 DOI: 10.1073/pnas.1203574109 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation