3U87

Structure of a chimeric construct of human CK2alpha and human CK2alpha' in complex with a non-hydrolysable ATP-analogue

Replaces:  3RP0

Summary for 3U87

• Entry DOI: 10.2210/pdb3u87/pdb
• Related: 1JWH 2PVR 3OFM 3U9C
• Descriptor: Casein kinase II subunit alpha, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ... (7 entities in total)
• Functional Keywords: protein kinase ck2 casein kinase 2, protein kinase fold, eukaryotic protein kinase, transferase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 84365.18

Authors

Niefind, K.,Raaf, J.,Issinger, O.-G.,Olsen, B. (deposition date: 2011-10-16, release date: 2012-05-30, Last modification date: 2023-09-13)

• Primary citation: Klopffleisch, K.,Issinger, O.G.,Niefind, K.; Low-density crystal packing of human protein kinase CK2 catalytic subunit in complex with resorufin or other ligands: a tool to study the unique hinge-region plasticity of the enzyme without packing bias.; Acta Crystallogr.,Sect.D, 68:883-892, 2012; PubMed: 22868753; DOI: 10.1107/S0907444912016587

Experimental method

X-RAY DIFFRACTION (2.9 Å)