3OFM

Structure of a human CK2alpha prime, the paralog isoform of the catalytic subunit of protein kinase CK2 from Homo sapiens

Summary for 3OFM

Entry DOI	10.2210/pdb3ofm/pdb
Related	1JWH 3BQC 3E3B
Descriptor	Casein kinase II subunit alpha', 3-(4,5,6,7-tetrabromo-1H-benzotriazol-1-yl)propan-1-ol, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	eukaryptic protein kinase fold, phospho transferase, atp binding, phosphorylation, cytoplasm and nucleus, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	41789.42
Authors	Bischoff, N.,Olsen, B.,Raaf, J.,Bretner, M.,Issinger, O.-G.,Niefind, K. (deposition date: 2010-08-15, release date: 2011-01-19, Last modification date: 2023-09-06)
Primary citation	Bischoff, N.,Olsen, B.,Raaf, J.,Bretner, M.,Issinger, O.G.,Niefind, K. Structural basis of the reduced affinity between the protein kinase CK2 subunits CK2alpha prime and CK2beta J.Mol.Biol., 407:1-12, 2011 Cited by PubMed: 21241709 DOI: 10.1016/j.jmb.2011.01.020 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation