3S9D
binary complex between IFNa2 and IFNAR2
Summary for 3S9D
Entry DOI | 10.2210/pdb3s9d/pdb |
Related | 3S8W 3S98 |
Descriptor | Interferon alpha-2, Interferon alpha/beta receptor 2, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | human, type i interferons, ifna2, ifnar2, sub-complex of the interferon signaling complex, signaling protein-receptor complex, signaling protein/receptor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P01563 Isoform 1: Membrane; Single-pass type I membrane protein. Isoform 2: Membrane; Single-pass type I membrane protein. Isoform 3: Secreted: P48551 |
Total number of polymer chains | 4 |
Total formula weight | 84417.90 |
Authors | Thomas, C.,Garcia, K.C. (deposition date: 2011-06-01, release date: 2011-08-31, Last modification date: 2023-09-13) |
Primary citation | Thomas, C.,Moraga, I.,Levin, D.,Krutzik, P.O.,Podoplelova, Y.,Trejo, A.,Lee, C.,Yarden, G.,Vleck, S.E.,Glenn, J.S.,Nolan, G.P.,Piehler, J.,Schreiber, G.,Garcia, K.C. Structural linkage between ligand discrimination and receptor activation by type I interferons. Cell(Cambridge,Mass.), 146:621-632, 2011 Cited by PubMed: 21854986DOI: 10.1016/j.cell.2011.06.048 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9999 Å) |
Structure validation
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