3S8W

D2 domain of human IFNAR2

Summary for 3S8W

Entry DOI	10.2210/pdb3s8w/pdb
Related	3S98 3S9D
Descriptor	Interferon alpha/beta receptor 2, CHLORIDE ION (3 entities in total)
Functional Keywords	human, type i interferons, receptor chain, ifnar2, fibronectin type iii module, part of type i interferon receptor chain, interferon, extracellular space, signaling protein receptor
Biological source	Homo sapiens (human)
Cellular location	Isoform 1: Membrane; Single-pass type I membrane protein. Isoform 2: Membrane; Single-pass type I membrane protein. Isoform 3: Secreted: P48551
Total number of polymer chains	3
Total formula weight	36212.73
Authors	Thomas, C.,Garcia, K.C. (deposition date: 2011-05-31, release date: 2011-08-31, Last modification date: 2012-03-21)
Primary citation	Thomas, C.,Moraga, I.,Levin, D.,Krutzik, P.O.,Podoplelova, Y.,Trejo, A.,Lee, C.,Yarden, G.,Vleck, S.E.,Glenn, J.S.,Nolan, G.P.,Piehler, J.,Schreiber, G.,Garcia, K.C. Structural linkage between ligand discrimination and receptor activation by type I interferons. Cell(Cambridge,Mass.), 146:621-632, 2011 Cited by PubMed: 21854986 DOI: 10.1016/j.cell.2011.06.048 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation