3RFM
Thermostabilised adenosine A2A receptor in complex with caffeine
Summary for 3RFM
Entry DOI | 10.2210/pdb3rfm/pdb |
Related | 3PWH 3REY |
Descriptor | Adenosine receptor A2a, CAFFEINE (2 entities in total) |
Functional Keywords | inverse agonist, 7tm, gpcr, signaling protein, g-protein, membrane protein |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane; Multi-pass membrane protein: P29274 |
Total number of polymer chains | 1 |
Total formula weight | 36673.29 |
Authors | Dore, A.S.,Robertson, N.,Errey, J.C.,Ng, I.,Hollenstein, K.,Tehan, B.,Hurrell, E.,Bennett, K.,Congreve, M.,Magnani, F.,Tate, C.G.,Weir, M.,Marshall, F.H. (deposition date: 2011-04-06, release date: 2011-09-07, Last modification date: 2023-11-01) |
Primary citation | Dore, A.S.,Robertson, N.,Errey, J.C.,Ng, I.,Hollenstein, K.,Tehan, B.,Hurrell, E.,Bennett, K.,Congreve, M.,Magnani, F.,Tate, C.G.,Weir, M.,Marshall, F.H. Structure of the adenosine A(2A) receptor in complex with ZM241385 and the xanthines XAC and caffeine Structure, 19:1283-1293, 2011 Cited by PubMed: 21885291DOI: 10.1016/j.str.2011.06.014 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.598 Å) |
Structure validation
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