3R2Y
MK2 kinase bound to Compound 1
Summary for 3R2Y
Entry DOI | 10.2210/pdb3r2y/pdb |
Related | 3R1N 3R2B 3R30 |
Descriptor | MAP kinase-activated protein kinase 2, MALONATE ION, 2-(2-QUINOLIN-3-YLPYRIDIN-4-YL)-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE, ... (4 entities in total) |
Functional Keywords | kinase domain, phosphotransferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 37437.13 |
Authors | Oubrie, A.,Leonard, P. (deposition date: 2011-03-15, release date: 2011-05-25, Last modification date: 2024-02-21) |
Primary citation | Barf, T.,Kaptein, A.,Wilde, S.,Heijden, R.,Someren, R.,Demont, D.,Schultz-Fademrecht, C.,Versteegh, J.,Zeeland, M.,Seegers, N.,Kazemier, B.,Kar, B.,Hoek, M.,Roos, J.,Klop, H.,Smeets, R.,Hofstra, C.,Hornberg, J.,Oubrie, A. Structure-based lead identification of ATP-competitive MK2 inhibitors. Bioorg.Med.Chem.Lett., 21:3818-3822, 2011 Cited by PubMed: 21565500DOI: 10.1016/j.bmcl.2011.04.018 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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