3QBC
Structure and design of a new pterin site inhibitor of S. aureus HPPK
Summary for 3QBC
| Entry DOI | 10.2210/pdb3qbc/pdb |
| Descriptor | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 2-amino-8-sulfanyl-1,9-dihydro-6H-purin-6-one (3 entities in total) |
| Functional Keywords | protein-inhibitor complex, ferredoxin-like fold, kinase, atp binding, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
| Biological source | Staphylococcus aureus |
| Total number of polymer chains | 2 |
| Total formula weight | 36974.58 |
| Authors | Peat, T.S.,Chhabra, S.,Swarbrick, J.D. (deposition date: 2011-01-12, release date: 2012-01-25, Last modification date: 2023-11-01) |
| Primary citation | Chhabra, S.,Dolezal, O.,Collins, B.M.,Newman, J.,Simpson, J.S.,Macreadie, I.G.,Fernley, R.,Peat, T.S.,Swarbrick, J.D. Structure of S. aureus HPPK and the discovery of a new substrate site inhibitor Plos One, 7:e29444-e29444, 2012 Cited by PubMed: 22276115DOI: 10.1371/journal.pone.0029444 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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