3Q8P
Human DNA polymerase iota incorporating dCTP opposite 8-oxo-guanine
Summary for 3Q8P
Entry DOI | 10.2210/pdb3q8p/pdb |
Related | 3Q8Q 3Q8R 3Q8S |
Descriptor | DNA polymerase iota, DNA (5'-D(*TP*CP*AP*(8OG)P*GP*GP*GP*TP*CP*CP*T)-3'), DNA (5'-D(P*AP*GP*GP*AP*CP*CP*C)-3'), ... (6 entities in total) |
Functional Keywords | dna polymerase, transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: Q9UNA4 |
Total number of polymer chains | 3 |
Total formula weight | 53031.72 |
Authors | Kirouac, K.N.,Ling, H. (deposition date: 2011-01-06, release date: 2011-02-23, Last modification date: 2024-02-21) |
Primary citation | Kirouac, K.N.,Ling, H. Unique active site promotes error-free replication opposite an 8-oxo-guanine lesion by human DNA polymerase iota. Proc.Natl.Acad.Sci.USA, 108:3210-3215, 2011 Cited by PubMed: 21300901DOI: 10.1073/pnas.1013909108 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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