3Q8R

Human DNA polymerase iota incorporating dGTP opposite 8-oxo-guanine

Summary for 3Q8R

• Entry DOI: 10.2210/pdb3q8r/pdb
• Related: 3Q8P 3Q8Q 3Q8S
• Descriptor: DNA polymerase iota, DNA (5'-D(*TP*CP*AP*(8OG)P*GP*GP*GP*TP*CP*CP*T)-3'), DNA (5'-D(P*AP*GP*GP*AP*CP*CP*C)-3'), ... (6 entities in total)
• Functional Keywords: dna polymerase, transferase-dna complex, transferase/dna
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: Q9UNA4
• Total number of polymer chains: 3
• Total formula weight: 53071.74

Authors

Kirouac, K.N.,Ling, H. (deposition date: 2011-01-06, release date: 2011-02-23, Last modification date: 2024-02-21)

• Primary citation: Kirouac, K.N.,Ling, H.; Unique active site promotes error-free replication opposite an 8-oxo-guanine lesion by human DNA polymerase iota.; Proc.Natl.Acad.Sci.USA, 108:3210-3215, 2011; PubMed: 21300901; DOI: 10.1073/pnas.1013909108

Experimental method

X-RAY DIFFRACTION (2.45 Å)