3PGC
Crystal Structure of HLA-DR1 with CLIP106-120, flipped peptide orientation
Summary for 3PGC
Entry DOI | 10.2210/pdb3pgc/pdb |
Related | 3PDO 3PGD |
Descriptor | HLA class II histocompatibility antigen, DR alpha chain, HLA class II histocompatibility antigen, DRB1-1 beta chain, HLA class II histocompatibility antigen gamma chain, ... (6 entities in total) |
Functional Keywords | mhc class ii, mhc ii, immune system, self antigen, invariant chain, clip |
Biological source | Homo sapiens (human) More |
Cellular location | Cell membrane; Single-pass type I membrane protein: P01903 P04229 Cell membrane; Single-pass type II membrane protein (Potential): P04233 |
Total number of polymer chains | 6 |
Total formula weight | 94548.77 |
Authors | Gunther, S.,Schlundt, A.,Sticht, J.,Roske, Y.,Heinemann, U.,Wiesmuller, K.-H.,Jung, G.,Falk, K.,Rotzschke, O.,Freund, C. (deposition date: 2010-11-01, release date: 2010-12-08, Last modification date: 2011-07-13) |
Primary citation | Gunther, S.,Schlundt, A.,Sticht, J.,Roske, Y.,Heinemann, U.,Wiesmuller, K.H.,Jung, G.,Falk, K.,Rotzschke, O.,Freund, C. Bidirectional binding of invariant chain peptides to an MHC class II molecule. Proc.Natl.Acad.Sci.USA, 107:22219-22224, 2010 Cited by PubMed: 21115828DOI: 10.1073/pnas.1014708107 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.66 Å) |
Structure validation
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