3P1E
Crystal structure of the bromodomain of human CREBBP in complex with dimethyl sulfoxide (DMSO)
Summary for 3P1E
Entry DOI | 10.2210/pdb3p1e/pdb |
Related | 3P1C 3P1D 3P1F |
Descriptor | CREB-binding protein, THIOCYANATE ION, DIMETHYL SULFOXIDE, ... (5 entities in total) |
Functional Keywords | structural genomics consortium, sgc, cbp, crebbp, creb binding protein isoform a, kat3a, rsts, rst, bromodomain, transcription |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: Q92793 |
Total number of polymer chains | 2 |
Total formula weight | 28700.14 |
Authors | Filippakopoulos, P.,Picaud, S.,Feletar, I.,Fedorov, O.,Muniz, J.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2010-09-30, release date: 2010-11-24, Last modification date: 2023-09-06) |
Primary citation | Filippakopoulos, P.,Picaud, S.,Feletar, I.,Fedorov, O.,Muniz, J.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) Crystal structure of the bromodomain of human CREBBP in complex with dimethyl sulfoxide (DMSO) To be Published, |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
Download full validation report