3P1C
Crystal structure of the bromodomain of human CREBBP in complex with acetylated lysine
Summary for 3P1C
| Entry DOI | 10.2210/pdb3p1c/pdb |
| Related | 3P1D 3P1E 3P1F |
| Descriptor | CREB-binding protein, N(6)-ACETYLLYSINE, THIOCYANATE ION, ... (5 entities in total) |
| Functional Keywords | structural genomics consortium, cbp, crebbp, creb binding protein isoform a, kat3a, rsts, rst, bromodomain, sgc, transcription |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: Q92793 |
| Total number of polymer chains | 2 |
| Total formula weight | 28920.33 |
| Authors | Filippakopoulos, P.,Picaud, S.,Feletar, I.,Fedorov, O.,Muniz, J.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2010-09-30, release date: 2010-11-24, Last modification date: 2023-12-06) |
| Primary citation | Filippakopoulos, P.,Picaud, S.,Mangos, M.,Keates, T.,Lambert, J.P.,Barsyte-Lovejoy, D.,Felletar, I.,Volkmer, R.,Muller, S.,Pawson, T.,Gingras, A.C.,Arrowsmith, C.H.,Knapp, S. Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149:214-231, 2012 Cited by PubMed: 22464331DOI: 10.1016/j.cell.2012.02.013 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.82 Å) |
Structure validation
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