3MDL
X-ray crystal structure of 1-arachidonoyl glycerol bound to the cyclooxygenase channel of cyclooxygenase-2
Summary for 3MDL
Entry DOI | 10.2210/pdb3mdl/pdb |
Related | 1CVU 1DIY 3HS5 3HS6 3HS7 3KRK |
Descriptor | Prostaglandin G/H synthase 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total) |
Functional Keywords | cox-2, cyclooxygenase-2, endocannabinoid, oxidoreductase |
Biological source | Mus musculus (mouse) |
Total number of polymer chains | 2 |
Total formula weight | 140147.05 |
Authors | Vecchio, A.J.,Malkowski, M.G. (deposition date: 2010-03-30, release date: 2011-04-13, Last modification date: 2023-09-06) |
Primary citation | Vecchio, A.J.,Malkowski, M.G. The structural basis of endocannabinoid oxygenation by cyclooxygenase-2. J.Biol.Chem., 286:20736-20745, 2011 Cited by PubMed: 21489986DOI: 10.1074/jbc.M111.230367 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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