3M04

Carbonic Anhydrase II in complex with novel sulfonamide inhibitor

Summary for 3M04

Entry DOI	10.2210/pdb3m04/pdb
Related	2Q38 3KIG 3KNE
Descriptor	Carbonic anhydrase 2, ZINC ION, phenyl N-sulfamoylmorpholine-4-carboximidoate, ... (5 entities in total)
Functional Keywords	10 stranded twisted beta-sheets, lyase, disease mutation, metal-binding, lyase-lyase inhibitor complex, lyase/lyase inhibitor
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm : P00918
Total number of polymer chains	1
Total formula weight	30514.47
Authors	Schulze Wischeler, J.,Heine, A.,Klebe, G.,Sandner, N.U. (deposition date: 2010-03-02, release date: 2011-05-25, Last modification date: 2024-02-28)
Primary citation	Schulze Wischeler, J.,Sandner, N.U.,Haake, M.,Supuran, C.,Heine, A.,Klebe, G. Structural investigation and inhibitor studies on Carbonic Anhydrase II To be Published,
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation