3KNE

Carbonic Anhydrase II H64C mutant in complex with an in situ formed triazole

Summary for 3KNE

• Entry DOI: 10.2210/pdb3kne/pdb
• Related: 3KIG
• Descriptor: Carbonic anhydrase 2, ZINC ION, (4-CARBOXYPHENYL)(CHLORO)MERCURY, ... (5 entities in total)
• Functional Keywords: 10 stranded; twisted beta-sheets; lyase; acetylation, metal-binding, click-chemistry, azide, alkyne, lyase
• Biological source: Homo sapiens
• Cellular location: Cytoplasm : P00918
• Total number of polymer chains: 1
• Total formula weight: 30682.73

Authors

Schulze-Wischeler, J.,Heine, A.,Klebe, G. (deposition date: 2009-11-12, release date: 2011-05-18, Last modification date: 2024-02-28)

• Primary citation: Schulze Wischeler, J.,Sun, D.,Sandner, N.U.,Linne, U.,Heine, A.,Koert, U.,Klebe, G.; Stereo- and Regioselective Azide/Alkyne Cycloadditions in Carbonic Anhydrase II via Tethering, Monitored by Crystallography and Mass Spectrometry.; Chemistry, 17:5842-5851, 2011; PubMed: 21506176; DOI: 10.1002/chem.201002437

Experimental method

X-RAY DIFFRACTION (1.35 Å)