3KTR
Structural basis of ataxin-2 recognition by poly(A)-binding protein
Summary for 3KTR
Entry DOI | 10.2210/pdb3ktr/pdb |
Related | 3KTP |
Descriptor | Polyadenylate-binding protein 1, Ataxin-2, CADMIUM ION, ... (5 entities in total) |
Functional Keywords | protein-protein complex, acetylation, alternative splicing, cytoplasm, methylation, mrna processing, mrna splicing, nucleus, phosphoprotein, rna-binding, spliceosome, neurodegeneration, parkinsonism, polymorphism, spinocerebellar ataxia, triplet repeat expansion, protein binding |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: P11940 Cytoplasm (By similarity): Q99700 |
Total number of polymer chains | 2 |
Total formula weight | 11665.54 |
Authors | Kozlov, G.,Gehring, K. (deposition date: 2009-11-25, release date: 2010-02-23, Last modification date: 2023-09-06) |
Primary citation | Kozlov, G.,Safaee, N.,Rosenauer, A.,Gehring, K. Structural basis of binding of P-body-associated proteins GW182 and ataxin-2 by the Mlle domain of poly(A)-binding protein. J.Biol.Chem., 285:13599-13606, 2010 Cited by PubMed: 20181956DOI: 10.1074/jbc.M109.089540 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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