3KFD
Ternary complex of TGF-b1 reveals isoform-specific ligand recognition and receptor recruitment in the superfamily
Summary for 3KFD
Entry DOI | 10.2210/pdb3kfd/pdb |
Related | 1M9Z 1REW 1TGJ 1TGK 2PJY 2TGI |
Descriptor | Transforming growth factor beta-1, TGF-beta receptor type-2, TGF-beta receptor type-1, ... (4 entities in total) |
Functional Keywords | tgf-beta, tgf-b1, tgf-beta receptor type-1, tgf-beta receptor type-2, tbrii, tbri, growth factor, receptor, serine/threonine-protein kinase, cytokine-cytokine receptor complex, cytokine/cytokine receptor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted, extracellular space, extracellular matrix: P01137 Membrane; Single-pass type I membrane protein: P37173 P36897 |
Total number of polymer chains | 12 |
Total formula weight | 141462.20 |
Authors | Radaev, S.,Sun, P.D. (deposition date: 2009-10-27, release date: 2010-03-02, Last modification date: 2023-09-06) |
Primary citation | Radaev, S.,Zou, Z.,Huang, T.,Lafer, E.M.,Hinck, A.P.,Sun, P.D. Ternary complex of transforming growth factor-beta1 reveals isoform-specific ligand recognition and receptor recruitment in the superfamily. J.Biol.Chem., 285:14806-14814, 2010 Cited by PubMed: 20207738DOI: 10.1074/jbc.M109.079921 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.995 Å) |
Structure validation
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