3K05

The crystal structure of MDC1 BRCT T2067D in complex with a minimal recognition tetrapeptide with an amidated C-terminus

Summary for 3K05

Entry DOI	10.2210/pdb3k05/pdb
Related	3K0H 3K0K
Descriptor	Mediator of DNA damage checkpoint protein 1, phospho peptide, GLYCEROL, ... (4 entities in total)
Functional Keywords	brct domain, protein-peptide complex, phospho protein binding, h2ax, dna damage response, cell cycle, dna damage, dna repair, nucleus, phosphoprotein, protein binding
Biological source	Homo sapiens (human) More
Cellular location	Nucleus : Q14676
Total number of polymer chains	4
Total formula weight	45287.88
Authors	Campbell, S.J.,Edwards, R.A.,Glover, J.N. (deposition date: 2009-09-24, release date: 2010-03-02, Last modification date: 2021-10-13)
Primary citation	Campbell, S.J.,Edwards, R.A.,Glover, J.N. Comparison of the Structures and Peptide Binding Specificities of the BRCT Domains of MDC1 and BRCA1 Structure, 18:167-176, 2010 Cited by PubMed: 20159462 DOI: 10.1016/j.str.2009.12.008 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.33 Å)

Structure validation