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1FOS
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BU of 1fos by Molmil
TWO HUMAN C-FOS:C-JUN:DNA COMPLEXES
Descriptor: C-JUN PROTO-ONCOGENE PROTEIN, DNA (5'-D(*AP*AP*TP*GP*GP*AP*TP*GP*AP*GP*TP*CP*AP*TP*AP*GP*GP*AP*GP*A)-3'), DNA (5'-D(*TP*TP*CP*TP*CP*CP*TP*AP*TP*GP*AP*CP*TP*CP*AP*TP*CP*CP*AP*T)-3'), ...
Authors:Glover, J.N.M, Harrison, S.C.
Deposit date:1995-03-07
Release date:1995-07-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Crystal structure of the heterodimeric bZIP transcription factor c-Fos-c-Jun bound to DNA.
Nature, 373, 1995
3D8A
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BU of 3d8a by Molmil
Co-crystal structure of TraM-TraD complex.
Descriptor: Protein traD, Relaxosome protein TraM
Authors:Glover, J.N.M, Lu, J, Wong, J.J, Edwards, R.A.
Deposit date:2008-05-22
Release date:2008-09-09
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural basis of specific TraD-TraM recognition during F plasmid-mediated bacterial conjugation.
Mol.Microbiol., 70, 2008
5U6K
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BU of 5u6k by Molmil
Crystal structure of TopBP1 BRCT4/5 in complex with a BLM phosphopeptide
Descriptor: Bloom Sydrome recQ helicase like protein (BLM), DNA topoisomerase 2-binding protein 1
Authors:Glover, J.N.M, Sun, L, Edwards, R.A.
Deposit date:2016-12-08
Release date:2017-10-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Insight into BLM Recognition by TopBP1.
Structure, 25, 2017
6DCX
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BU of 6dcx by Molmil
iASPP-PP-1c structure and targeting of p53
Descriptor: RelA-associated inhibitor, Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
Authors:Glover, J.N.M, Zhou, Y, Edwards, R.A.
Deposit date:2018-05-08
Release date:2019-05-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.408 Å)
Cite:Flexible Tethering of ASPP Proteins Facilitates PP-1c Catalysis.
Structure, 27, 2019
8UK7
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BU of 8uk7 by Molmil
Periplasmic domain of Escherichia coli CpxA
Descriptor: Sensor histidine kinase CpxA
Authors:Glover, M.J.N, Murray, C.R.A, Edwards, R.A, Thede, G.L.
Deposit date:2023-10-12
Release date:2023-10-25
Last modified:2024-04-17
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The sensor of the bacterial histidine kinase CpxA is a novel dimer of extracytoplasmic Per-ARNT-Sim (PAS) domains.
J.Biol.Chem., 2024
3U7G
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BU of 3u7g by Molmil
Crystal structure of mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTAp)
Descriptor: Bifunctional polynucleotide phosphatase/kinase, DNA, GLYCEROL, ...
Authors:Coquelle, N, Havali, Z, Bernstein, N, Green, R, Glover, J.N.M.
Deposit date:2011-10-13
Release date:2011-12-14
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substrates.
Proc.Natl.Acad.Sci.USA, 108, 2011
3U7E
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BU of 3u7e by Molmil
Crystal structure of mPNKP catalytic fragment (D170A)
Descriptor: Bifunctional polynucleotide phosphatase/kinase, GLYCEROL, MAGNESIUM ION, ...
Authors:Coquelle, N, Havali, Z, Bernstein, N, Green, R, Glover, J.N.M.
Deposit date:2011-10-13
Release date:2011-12-14
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substrates.
Proc.Natl.Acad.Sci.USA, 108, 2011
3U7F
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BU of 3u7f by Molmil
Crystal structure of mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTCp)
Descriptor: Bifunctional polynucleotide phosphatase/kinase, DNA, GLYCEROL, ...
Authors:Coquelle, N, Havali, Z, Bernstein, N, Green, R, Glover, J.N.M.
Deposit date:2011-10-13
Release date:2011-12-14
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substrates.
Proc.Natl.Acad.Sci.USA, 108, 2011
4NRG
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BU of 4nrg by Molmil
Crystal Structure of a human Mms2/Ubc13 D118G mutant
Descriptor: Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2
Authors:Hodge, C.D, Edwards, R.A, Glover, J.N.M.
Deposit date:2013-11-26
Release date:2014-12-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Stochastic gate dynamics regulate the catalytic activity of ubiquitination enzymes.
J.Am.Chem.Soc., 136, 2014
1MNN
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BU of 1mnn by Molmil
Structure of the sporulation specific transcription factor Ndt80 bound to DNA
Descriptor: 5'-D(*AP*GP*TP*TP*TP*TP*TP*GP*TP*GP*TP*CP*GP*C)-3', 5'-D(*TP*GP*CP*GP*AP*CP*AP*CP*AP*AP*AP*AP*AP*C)-3', NDT80 protein
Authors:Lamoureux, J.S, Stuart, D, Tsang, R, Wu, C, Glover, J.N.
Deposit date:2002-09-05
Release date:2002-11-20
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure of the sporulation-specific transcription factor Ndt80 bound to DNA
Embo J., 21, 2002
4ONM
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BU of 4onm by Molmil
Crystal structure of human Mms2/Ubc13 - NSC697923
Descriptor: 2-[(4-methylphenyl)sulfonyl]-5-nitrofuran, GLYCEROL, Ubiquitin-conjugating enzyme E2 N, ...
Authors:Hodge, C.D, Edwards, R.A, Glover, J.N.M.
Deposit date:2014-01-28
Release date:2015-05-06
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting.
Acs Chem.Biol., 10, 2015
3PXE
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BU of 3pxe by Molmil
Impact of BRCA1 BRCT domain missense substitutions on phospho-peptide recognition: E1836K
Descriptor: Breast cancer type 1 susceptibility protein, phospho peptide
Authors:Coquelle, N, Green, R, Glover, J.N.M.
Deposit date:2010-12-09
Release date:2011-04-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Impact of BRCA1 BRCT Domain Missense Substitutions on Phosphopeptide Recognition.
Biochemistry, 50, 2011
3PXD
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BU of 3pxd by Molmil
Impact of BRCA1 BRCT domain missense substitutions on phospho-peptide recognition: R1835P
Descriptor: Breast cancer type 1 susceptibility protein, NICKEL (II) ION, SULFATE ION
Authors:Coquelle, N, Green, R, Glover, J.N.M.
Deposit date:2010-12-09
Release date:2011-04-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Impact of BRCA1 BRCT Domain Missense Substitutions on Phosphopeptide Recognition.
Biochemistry, 50, 2011
3PXA
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BU of 3pxa by Molmil
Impact of BRCA1 BRCT domain missense substitutions on phospho-peptide recognition: G1656D
Descriptor: Breast cancer type 1 susceptibility protein, NICKEL (II) ION, SULFATE ION
Authors:Coquelle, N, Green, R, Glover, J.N.M.
Deposit date:2010-12-09
Release date:2011-04-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Impact of BRCA1 BRCT Domain Missense Substitutions on Phosphopeptide Recognition.
Biochemistry, 50, 2011
3PXB
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BU of 3pxb by Molmil
Impact of BRCA1 BRCT domain missense substitutions on phospho-peptide recognition: T1700A
Descriptor: Breast cancer type 1 susceptibility protein, NICKEL (II) ION, SULFATE ION
Authors:Coquelle, N, Green, R, Glover, J.N.M.
Deposit date:2010-12-09
Release date:2011-04-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Impact of BRCA1 BRCT Domain Missense Substitutions on Phosphopeptide Recognition.
Biochemistry, 50, 2011
3PXC
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BU of 3pxc by Molmil
Impact of BRCA1 BRCT domain missense substitutions on phospho-peptide recognition: R1699Q
Descriptor: Breast cancer type 1 susceptibility protein, NICKEL (II) ION, SULFATE ION
Authors:Coquelle, N, Green, R, Glover, J.N.M.
Deposit date:2010-12-09
Release date:2011-04-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Impact of BRCA1 BRCT Domain Missense Substitutions on Phosphopeptide Recognition.
Biochemistry, 50, 2011
3U7H
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BU of 3u7h by Molmil
Crystal structure of mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTTp)
Descriptor: Bifunctional polynucleotide phosphatase/kinase, DNA, GLYCEROL, ...
Authors:Coquelle, N, Havali, Z, Bernstein, N, Green, R, Glover, J.N.M.
Deposit date:2011-10-13
Release date:2011-12-14
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substrates.
Proc.Natl.Acad.Sci.USA, 108, 2011
2G9E
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BU of 2g9e by Molmil
Protonation-mediated structural flexibility in the F conjugation regulatory protein, TRAM
Descriptor: Protein traM
Authors:Lu, J, Edwards, R.A, Wong, J.J, Manchak, J, Scott, P.G, Frost, L.S, Glover, J.N.
Deposit date:2006-03-06
Release date:2006-06-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Protonation-mediated structural flexibility in the F conjugation regulatory protein, TraM.
Embo J., 25, 2006
2G7O
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BU of 2g7o by Molmil
Protonation-mediated structural flexibility in the F conjugation regulatory protein, TraM
Descriptor: Protein traM
Authors:Lu, J, Edwards, R.A, Wong, J.J, Manchak, J, Scott, P.G, Frost, L.S, Glover, J.N.
Deposit date:2006-02-28
Release date:2006-06-13
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Protonation-mediated structural flexibility in the F conjugation regulatory protein, TraM.
Embo J., 25, 2006
2RH3
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BU of 2rh3 by Molmil
Crystal structure of plasmid pTiC58 VirC2
Descriptor: Protein virC2
Authors:Lu, J, Glover, J.N.M.
Deposit date:2007-10-05
Release date:2008-10-14
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Agrobacterium tumefaciens VirC2 enhances T-DNA transfer and virulence through its C-terminal ribbon-helix-helix DNA-binding fold
Proc.Natl.Acad.Sci.USA, 106, 2009
3AL3
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BU of 3al3 by Molmil
Crystal Structure of TopBP1 BRCT7/8-BACH1 peptide complex
Descriptor: DNA topoisomerase 2-binding protein 1, FORMIC ACID, Peptide of Fanconi anemia group J protein
Authors:Leung, C.C, Glover, J.N.
Deposit date:2010-07-22
Release date:2010-12-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Molecular basis of BACH1/FANCJ recognition by TopBP1 in DNA replication checkpoint control
J.Biol.Chem., 286, 2011
3AL2
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BU of 3al2 by Molmil
Crystal Structure of TopBP1 BRCT7/8
Descriptor: DNA topoisomerase 2-binding protein 1, SULFATE ION
Authors:Leung, C.C, Glover, J.N.
Deposit date:2010-07-22
Release date:2010-12-01
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular basis of BACH1/FANCJ recognition by TopBP1 in DNA replication checkpoint control
J.Biol.Chem., 286, 2011
4NR3
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BU of 4nr3 by Molmil
Crystal Structure of a human Mms2/Ubc13 L121G mutant
Descriptor: Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2
Authors:Hodge, C.D, Edwards, R.A, Glover, J.N.M.
Deposit date:2013-11-26
Release date:2014-12-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.802 Å)
Cite:Stochastic gate dynamics regulate the catalytic activity of ubiquitination enzymes.
J.Am.Chem.Soc., 136, 2014
4NRI
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BU of 4nri by Molmil
Crystal Structure of a human Mms2/Ubc13 A122G mutant
Descriptor: GLYCEROL, Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2
Authors:Hodge, C.D, Edwards, R.A, Glover, J.N.M.
Deposit date:2013-11-26
Release date:2014-12-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Stochastic gate dynamics regulate the catalytic activity of ubiquitination enzymes.
J.Am.Chem.Soc., 136, 2014
4WHV
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BU of 4whv by Molmil
E3 ubiquitin-protein ligase RNF8 in complex with Ubiquitin-conjugating enzyme E2 N and Polyubiquitin-B
Descriptor: E3 ubiquitin-protein ligase RNF8, Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 N, ...
Authors:Hodge, C.D, Edwards, R.A, Glover, J.N.M.
Deposit date:2014-09-23
Release date:2015-09-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (8.3 Å)
Cite:RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment.
J.Biol.Chem., 291, 2016

 

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