3IIF
Crystal structure of the macro domain of human histone macroH2A1.1 in complex with ADP-ribose (form B)
Summary for 3IIF
| Entry DOI | 10.2210/pdb3iif/pdb |
| Related | 1ZR3 2FXK 3IID |
| Descriptor | Core histone macro-H2A.1, Isoform 1, ADENOSINE-5-DIPHOSPHORIBOSE (3 entities in total) |
| Functional Keywords | histone, chromatin, macro domain, chromatin regulator, chromosomal protein, dna-binding, isopeptide bond, methylation, nucleosome core, nucleus, phosphoprotein, gene regulation |
| Biological source | Homo sapiens (human) |
| Cellular location | Nucleus: O75367-2 |
| Total number of polymer chains | 3 |
| Total formula weight | 68500.95 |
| Authors | Hothorn, M.,Bortfeld, M.,Ladurner, A.G.,Scheffzek, K. (deposition date: 2009-07-31, release date: 2009-08-18, Last modification date: 2023-09-06) |
| Primary citation | Timinszky, G.,Till, S.,Hassa, P.O.,Hothorn, M.,Kustatscher, G.,Nijmeijer, B.,Colombelli, J.,Altmeyer, M.,Stelzer, E.H.,Scheffzek, K.,Hottiger, M.O.,Ladurner, A.G. A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation. Nat.Struct.Mol.Biol., 16:923-929, 2009 Cited by PubMed: 19680243DOI: 10.1038/nsmb.1664 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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