3IID

Crystal structure of the macro domain of human histone macroH2A1.1 in complex with ADP-ribose (form A)

Summary for 3IID

Entry DOI	10.2210/pdb3iid/pdb
Related	1ZR3 2FXK 3IIF
Descriptor	Core histone macro-H2A.1, Isoform 1, ADENOSINE-5-DIPHOSPHORIBOSE, NITRATE ION, ... (4 entities in total)
Functional Keywords	histone, chromatin, macro domain, chromatin regulator, chromosomal protein, dna-binding, isopeptide bond, methylation, nucleosome core, nucleus, phosphoprotein, gene regulation
Biological source	Homo sapiens (human)
Cellular location	Nucleus: O75367-2
Total number of polymer chains	1
Total formula weight	22895.65
Authors	Hothorn, M.,Bortfeld, M.,Ladurner, A.G.,Scheffzek, K. (deposition date: 2009-07-31, release date: 2009-08-18, Last modification date: 2023-09-06)
Primary citation	Timinszky, G.,Till, S.,Hassa, P.O.,Hothorn, M.,Kustatscher, G.,Nijmeijer, B.,Colombelli, J.,Altmeyer, M.,Stelzer, E.H.,Scheffzek, K.,Hottiger, M.O.,Ladurner, A.G. A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation. Nat.Struct.Mol.Biol., 16:923-929, 2009 Cited by PubMed: 19680243 DOI: 10.1038/nsmb.1664 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation