3G8E

Crystal Structure of Rattus norvegicus Visfatin/PBEF/Nampt in Complex with an FK866-based inhibitor

Summary for 3G8E

• Entry DOI: 10.2210/pdb3g8e/pdb
• Related: 2G96 2G97
• Descriptor: Nicotinamide phosphoribosyltransferase, 3-[(1E)-3-oxo-3-({4-[1-(phenylcarbonyl)piperidin-4-yl]butyl}amino)prop-1-en-1-yl]-1-beta-D-ribofuranosylpyridinium (2 entities in total)
• Functional Keywords: protein-ligand complex, is001, cytoplasm, glycosyltransferase, nucleus, phosphoprotein, pyridine nucleotide biosynthesis, transferase
• Biological source: Rattus norvegicus (rat)
• Cellular location: Cytoplasm: Q80Z29
• Total number of polymer chains: 2
• Total formula weight: 112074.63

Authors

Kang, G.B.,Bae, M.H.,Kim, M.K.,Im, I.,Kim, Y.C.,Eom, S.H. (deposition date: 2009-02-12, release date: 2009-08-18, Last modification date: 2023-11-01)

• Primary citation: Kang, G.B.,Bae, M.H.,Kim, M.K.,Im, I.,Kim, Y.C.,Eom, S.H.; Crystal structure of Rattus norvegicus Visfatin/PBEF/Nampt in complex with an FK866-based inhibitor; Mol.Cells, 27:667-671, 2009; PubMed: 19533035; DOI: 10.1007/s10059-009-0088-x

Experimental method

X-RAY DIFFRACTION (3 Å)