2G97

Crystal Structure of Visfatin/Pre-B Cell Colony Enhancing Factor 1/Nicotinamide Phosphoribosyltransferase In Complex with the Specific Inhibitor FK-866

Summary for 2G97

• Entry DOI: 10.2210/pdb2g97/pdb
• Related: 2g95 2g96
• Descriptor: Nicotinamide phosphoribosyltransferase, (2E)-N-{4-[1-(benzenecarbonyl)piperidin-4-yl]butyl}-3-(pyridin-3-yl)prop-2-enamide (3 entities in total)
• Functional Keywords: visfatin, pbef, namprtase, fk-866, rattus norvegicus, transferase
• Biological source: Rattus norvegicus (Norway rat)
• Cellular location: Nucleus : Q80Z29
• Total number of polymer chains: 2
• Total formula weight: 111808.39

Authors

Kim, M.-K.,Eom, S.H. (deposition date: 2006-03-05, release date: 2006-08-01, Last modification date: 2023-10-25)

• Primary citation: Kim, M.-K.,Lee, J.H.,Kim, H.,Park, S.J.,Kim, S.H.,Kang, G.B.,Lee, Y.S.,Kim, J.B.,Kim, K.K.,Suh, S.W.,Eom, S.H.; Crystal Structure of Visfatin/Pre-B Cell Colony-enhancing Factor 1/Nicotinamide Phosphoribosyltransferase, Free and in Complex with the Anti-cancer Agent FK-866; J.Mol.Biol., 362:66-77, 2006; PubMed: 16901503; DOI: 10.1016/j.jmb.2006.06.082

Experimental method

X-RAY DIFFRACTION (2.9 Å)