2G97
Crystal Structure of Visfatin/Pre-B Cell Colony Enhancing Factor 1/Nicotinamide Phosphoribosyltransferase In Complex with the Specific Inhibitor FK-866
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Nicotinamide phosphoribosyltransferase | polymer | 491 | 55512.7 | 2 | UniProt (Q80Z29) Pfam (PF18127) Pfam (PF04095) In PDB | Rattus norvegicus (Norway rat) | NAmPRTase, Nampt, Pre-B-cell colony-enhancing factor 1 homolog, PBEF, Visfatin |
2 | A, B | (2E)-N-{4-[1-(benzenecarbonyl)piperidin-4-yl]butyl}-3-(pyridin-3-yl)prop-2-enamide | non-polymer | 391.5 | 2 | Chemie (DGB) | |||
3 | water | water | 18.0 | 117 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 111025.4 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 783.0 | |
All* | Total formula weight | 111808.4 |