3D85
Crystal structure of IL-23 in complex with neutralizing FAB
Summary for 3D85
Entry DOI | 10.2210/pdb3d85/pdb |
Related | 1F45 3D87 |
Descriptor | FAB of antibody 7G10, light chain, FAB of antibody 7G10, heavy chain, Interleukin-23 subunit p19, ... (7 entities in total) |
Functional Keywords | interleukin-23, fab, immune system-cytokine complex, immune system/cytokine |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: Q9NPF7 P29460 |
Total number of polymer chains | 4 |
Total formula weight | 102027.23 |
Authors | Beyer, B.M.,Ingram, R.,Ramanathan, L.,Reichert, P.,Le, H.,Madison, V. (deposition date: 2008-05-22, release date: 2008-09-02, Last modification date: 2023-08-30) |
Primary citation | Beyer, B.M.,Ingram, R.,Ramanathan, L.,Reichert, P.,Le, H.V.,Madison, V.,Orth, P. Crystal structures of the pro-inflammatory cytokine interleukin-23 and its complex with a high-affinity neutralizing antibody J.Mol.Biol., 382:942-955, 2008 Cited by PubMed: 18708069DOI: 10.1016/j.jmb.2008.08.001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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