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1F45

HUMAN INTERLEUKIN-12

Summary for 1F45

Related1F42 
DescriptorINTERLEUKIN-12 BETA CHAIN COMPLEX WITH INTERLEUKIN-12 ALPHA CHAIN
Functional Keywordsinterleukin, cytokine, CYTOKINE-CYTOKINE COMPLEX,CYTOKINE/CYTOKINE
Biological sourceHomo sapiens (human)
Total number of polymer chains3
Total molecular weight57895.02
Authors
Yoon, C.,Johnston, S.C.,Tang, J.,Tobin, J.F.,Somers, W.S. (deposition date: 2000-06-07, release date: 2001-06-20, modification date: 2011-07-13)
Primary citation
Yoon, C.,Johnston, S.C.,Tang, J.,Stahl, M.,Tobin, J.F.,Somers, W.S.
Charged residues dominate a unique interlocking topography in the heterodimeric cytokine interleukin-12.
EMBO J., 19:3530-3541, 2000
PubMed: 10899108
DOI: 10.1093/emboj/19.14.3530
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.8 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers335.8%13.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolutionDownload full validation report

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entries available on 2014-12-17
00:00 UTC / 09:00 JST