3D81
Sir2-S-alkylamidate complex crystal structure
Summary for 3D81
Entry DOI | 10.2210/pdb3d81/pdb |
Related | 3D4B |
Descriptor | NAD-dependent deacetylase, S-alkylamidate intermediate, ZINC ION, ... (4 entities in total) |
Functional Keywords | rossmann fold, nad dependent deacetylase, cytoplasm, hydrolase, metal-binding, nad, zinc |
Biological source | Thermotoga maritima |
Cellular location | Cytoplasm : Q9WYW0 |
Total number of polymer chains | 2 |
Total formula weight | 29283.92 |
Authors | Hawse, W.F.,Hoff, K.G.,Fatkins, D.,Daines, A.,Zubkova, O.V.,Schramm, V.L.,Zheng, W.,Wolberger, C. (deposition date: 2008-05-22, release date: 2008-09-30, Last modification date: 2023-11-15) |
Primary citation | Hawse, W.F.,Hoff, K.G.,Fatkins, D.G.,Daines, A.,Zubkova, O.V.,Schramm, V.L.,Zheng, W.,Wolberger, C. Structural insights into intermediate steps in the Sir2 deacetylation reaction. Structure, 16:1368-1377, 2008 Cited by PubMed: 18786399DOI: 10.1016/j.str.2008.05.015 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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