3D0V

Crystal structure of the HIV-1 Cross Neutralizing Monoclonal Antibody 2F5 in complex with gp41 Peptide LLELDKWASLW

Summary for 3D0V

• Entry DOI: 10.2210/pdb3d0v/pdb
• Related: 1tjh 2p8l 2p8m 2p8p 3d0l
• Descriptor: 2F5 Fab heavy chain, 2F5 Fab light chain, gp41 peptide LLELDKWASLW, ... (4 entities in total)
• Functional Keywords: 2f5, hiv, gp41, antibody, neutralizing, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 49984.15

Authors

Bryson, S.,Julien, J.P.,Pai, E.F. (deposition date: 2008-05-02, release date: 2008-07-29, Last modification date: 2023-08-30)

• Primary citation: Julien, J.P.,Bryson, S.,Nieva, J.L.,Pai, E.F.; Structural details of HIV-1 recognition by the broadly neutralizing monoclonal antibody 2F5: epitope conformation, antigen-recognition loop mobility, and anion-binding site.; J.Mol.Biol., 384:377-392, 2008; PubMed: 18824005; DOI: 10.1016/j.jmb.2008.09.024

Experimental method

X-RAY DIFFRACTION (2.05 Å)