3CYF

Crystal Structure of E18N DJ-1

Summary for 3CYF

Entry DOI	10.2210/pdb3cyf/pdb
Related	1P5F 2OR3 3CY6 3CZ9 3CZA
Descriptor	Protein DJ-1 (2 entities in total)
Functional Keywords	reactive cysteine, chaperone, nucleus, oncogene, oxidation, parkinson disease, unknown function
Biological source	Homo sapiens (human)
Cellular location	Cell membrane; Lipid-anchor: Q99497
Total number of polymer chains	1
Total formula weight	21005.19
Authors	Witt, A.C.,Lakshminarasimhan, M.,Remington, B.C.,Hasim, S.,Pozharski, E.,Wilson, M.A. (deposition date: 2008-04-25, release date: 2008-07-01, Last modification date: 2023-08-30)
Primary citation	Witt, A.C.,Lakshminarasimhan, M.,Remington, B.C.,Hasim, S.,Pozharski, E.,Wilson, M.A. Cysteine pKa depression by a protonated glutamic acid in human DJ-1. Biochemistry, 47:7430-7440, 2008 Cited by PubMed: 18570440 DOI: 10.1021/bi800282d PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation