3CZA

Crystal Structure of E18D DJ-1

Summary for 3CZA

Entry DOI	10.2210/pdb3cza/pdb
Related	1P5F 2OR3 3CY6 3CYF 3CZ9
Descriptor	Protein DJ-1, MALONIC ACID (3 entities in total)
Functional Keywords	reactive cysteine, chaperone, nucleus, oncogene, oxidation, parkinson disease, unknown function
Biological source	Homo sapiens (Human)
Cellular location	Cell membrane ; Lipid-anchor : Q99497
Total number of polymer chains	1
Total formula weight	21078.24
Authors	Witt, A.C.,Lakshminarasimhan, M.,Remington, B.C.,Hashim, S.,Pozharski, E.,Wilson, M.A. (deposition date: 2008-04-28, release date: 2008-07-01, Last modification date: 2023-08-30)
Primary citation	Witt, A.C.,Lakshminarasimhan, M.,Remington, B.C.,Hasim, S.,Pozharski, E.,Wilson, M.A. Cysteine pKa depression by a protonated glutamic acid in human DJ-1. Biochemistry, 47:7430-7440, 2008 Cited by PubMed: 18570440 DOI: 10.1021/bi800282d PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.2 Å)

Structure validation