3CQS

A 3'-OH, 2',5'-phosphodiester substitution in the hairpin ribozyme active site reveals similarities with protein ribonucleases

Summary for 3CQS

Entry DOI	10.2210/pdb3cqs/pdb
Related	11BA 2P7E 2P7F
Descriptor	13-mer substrate strand with 3'-OH, 2',5'-phosphodiester covalently linking 5th and 6th nucleotides, 29-mer ribozyme strand with S9L synthetic linker at 13th position, 19-mer ribozyme strand, ... (5 entities in total)
Functional Keywords	2', 5' phosphodiester; hairpin ribozyme; reaction-intermediate; transition-state stabilization; ribonuclease; phosphoryl-transfer, rna
Total number of polymer chains	3
Total formula weight	19968.14
Authors	Torelli, A.T.,Spitale, R.C.,Krucinska, J.,Wedekind, J.E. (deposition date: 2008-04-03, release date: 2008-05-20, Last modification date: 2023-08-30)
Primary citation	Torelli, A.T.,Spitale, R.C.,Krucinska, J.,Wedekind, J.E. Shared traits on the reaction coordinates of ribonuclease and an RNA enzyme Biochem.Biophys.Res.Commun., 371:154-158, 2008 Cited by PubMed: 18423397 DOI: 10.1016/j.bbrc.2008.04.036 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation