3CIK
Human GRK2 in Complex with Gbetagamma subunits
Summary for 3CIK
Entry DOI | 10.2210/pdb3cik/pdb |
Related | 1BX6 1OMW 3CIL |
Descriptor | Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (5 entities in total) |
Functional Keywords | protein kinase, complex, g protein, receptor, wd40 repeat, atp-binding, nucleotide-binding, serine/threonine-protein kinase, transferase, transducer, wd repeat, lipoprotein, membrane, phosphoprotein, prenylation, transferase-signaling protein complex, transferase/signaling protein |
Biological source | Homo sapiens (Human) More |
Cellular location | Cell membrane; Lipid-anchor; Cytoplasmic side (Potential): P63212 |
Total number of polymer chains | 3 |
Total formula weight | 125540.53 |
Authors | Tesmer, J.J.G.,Lodowski, D.T. (deposition date: 2008-03-11, release date: 2009-02-17, Last modification date: 2012-03-07) |
Primary citation | Tesmer, J.J.,Tesmer, V.M.,Lodowski, D.T.,Steinhagen, H.,Huber, J. Structure of human G protein-coupled receptor kinase 2 in complex with the kinase inhibitor balanol. J.Med.Chem., 53:1867-1870, 2010 Cited by PubMed: 20128603DOI: 10.1021/jm9017515 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.75 Å) |
Structure validation
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