3C8N
Crystal structure of apo-FGD1 from Mycobacterium tuberculosis
Summary for 3C8N
Entry DOI | 10.2210/pdb3c8n/pdb |
Related | 3B4Y |
Descriptor | Probable F420-dependent glucose-6-phosphate dehydrogenase FGD1 (2 entities in total) |
Functional Keywords | tim barrel, non-prolyl cis-peptide, oxidoreductase |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 4 |
Total formula weight | 158760.50 |
Authors | Bashiri, G.,Squire, C.J.,Moreland, N.J.,Baker, E.N. (deposition date: 2008-02-12, release date: 2008-04-22, Last modification date: 2021-10-20) |
Primary citation | Bashiri, G.,Squire, C.J.,Moreland, N.J.,Baker, E.N. Crystal structures of F420-dependent glucose-6-phosphate dehydrogenase FGD1 involved in the activation of the anti-tuberculosis drug candidate PA-824 reveal the basis of coenzyme and substrate binding. J.Biol.Chem., 283:17531-17541, 2008 Cited by PubMed: 18434308DOI: 10.1074/jbc.M801854200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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