3AV6

Crystal structure of mouse DNA methyltransferase 1 with AdoMet

3AV6 の概要

• エントリーDOI: 10.2210/pdb3av6/pdb
• 分子名称: DNA (cytosine-5)-methyltransferase 1, ZINC ION, S-ADENOSYLMETHIONINE (3 entities in total)
• 機能のキーワード: cxxc-type zinc finger/c5-methyltransferase family, methylates cpg residues, preferentially methylates hemimethylated dna, dna binding, hemi-methylation, nucleus, transferase
• 由来する生物種: Mus musculus (mouse)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 151456.54

構造登録者

Takeshita, K.,Suetake, I.,Yamashita, E.,Suga, M.,Narita, H.,Nakagawa, A.,Tajima, S. (登録日: 2011-02-22, 公開日: 2011-05-04, 最終更新日: 2023-11-01)

• 主引用文献: Takeshita, K.,Suetake, I.,Yamashita, E.,Suga, M.,Narita, H.,Nakagawa, A.,Tajima, S.; Structural insight into maintenance methylation by mouse DNA methyltransferase 1 (Dnmt1).; Proc.Natl.Acad.Sci.USA, 108:9055-9059, 2011; PubMed: 21518897; DOI: 10.1073/pnas.1019629108

実験手法

X-RAY DIFFRACTION (3.09 Å)