2Y3I
The structure of the fully closed conformation of human PGK in complex with L-ADP, 3PG and the TSA aluminium tetrafluoride
Summary for 2Y3I
Entry DOI | 10.2210/pdb2y3i/pdb |
Related | 2WZB 2WZC 2WZD 2X13 2X14 2X15 2XE6 2XE7 2XE8 |
Descriptor | PHOSPHOGLYCERATE KINASE 1, MAGNESIUM ION, CHLORIDE ION, ... (7 entities in total) |
Functional Keywords | transferase, aids, hepatitis, cancer, l-nucleoside analogues, glycolysis |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 2 |
Total formula weight | 90706.98 |
Authors | Bowler, M.W.,Chaloin, L.,Lionne, C. (deposition date: 2010-12-21, release date: 2011-04-27, Last modification date: 2023-12-20) |
Primary citation | Lallemand, P.,Chaloin, L.,Roy, B.,Barman, T.,Bowler, M.W.,Lionne, C. Interaction of Human 3-Phosphoglycerate Kinase with its Two Substrates: Is Substrate Antagonism a Kinetic Advantage? J.Mol.Biol., 409:742-, 2011 Cited by PubMed: 21549713DOI: 10.1016/J.JMB.2011.04.048 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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