2X13

The catalytically active fully closed conformation of human phosphoglycerate kinase in complex with ADP and 3phosphoglycerate

Summary for 2X13

Entry DOI	10.2210/pdb2x13/pdb
Related	2WZB 2WZC 2WZD 2X14 2X15 2XE6 2XE7 2XE8 2Y3I
Descriptor	PHOSPHOGLYCERATE KINASE 1, MAGNESIUM ION, 3-PHOSPHOGLYCERIC ACID, ... (5 entities in total)
Functional Keywords	transition state analogue, hereditary hemolytic anemia, atp-binding, kinase, glycolysis, transferase, disease mutation
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Cytoplasm: P00558
Total number of polymer chains	1
Total formula weight	45178.99
Authors	Bowler, M.W.,Cliff, M.J.,Marston, J.P.M.,Baxter, N.J.,Hownslow, A.M.H.,Varga, A.V.,Szabo, J.,Vas, M.,Blackburn, G.M.,Waltho, J.P. (deposition date: 2009-12-21, release date: 2010-12-29, Last modification date: 2024-08-21)
Primary citation	Pellegrini, E.,Juyoux, P.,von Velsen, J.,Baxter, N.J.,Dannatt, H.R.W.,Jin, Y.,Cliff, M.J.,Waltho, J.P.,Bowler, M.W. Metal fluorides-multi-functional tools for the study of phosphoryl transfer enzymes, a practical guide. Structure, 2024 Cited by PubMed: 39106858 DOI: 10.1016/j.str.2024.07.007 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.74 Å)

Structure validation