2X8Z

Crystal structure of AnCE-captopril complex

Summary for 2X8Z

• Entry DOI: 10.2210/pdb2x8z/pdb
• Related: 1J36 1J37 1J38 2X8Y 2X90 2X91 2X92 2X93 2X94 2X95 2X96 2X97
• Descriptor: ANGIOTENSIN CONVERTING ENZYME, beta-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, L-CAPTOPRIL, ... (6 entities in total)
• Functional Keywords: hydrolase, ace inhibitor, zinc metallopeptidase
• Biological source: DROSOPHILA MELANOGASTER
• Total number of polymer chains: 1
• Total formula weight: 70950.68

Authors

Akif, M.,Georgiadis, D.,Mahajan, A.,Dive, V.,Sturrock, E.D.,Isaac, R.E.,Acharya, K.R. (deposition date: 2010-03-14, release date: 2010-06-02, Last modification date: 2023-12-20)

• Primary citation: Akif, M.,Georgiadis, D.,Mahajan, A.,Dive, V.,Sturrock, E.D.,Isaac, R.E.,Acharya, K.R.; High Resolution Crystal Structures of Drosophila Melanogaster Angiotensin Converting Enzyme in Complex with Novel Inhibitors and Anti- Hypertensive Drugs.; J.Mol.Biol., 400:502-, 2010; PubMed: 20488190; DOI: 10.1016/J.JMB.2010.05.024

Experimental method

X-RAY DIFFRACTION (1.98 Å)