2X91

Crystal structure of AnCE-lisinopril complex

Summary for 2X91

Entry DOI	10.2210/pdb2x91/pdb
Related	1J36 1J37 1J38 2X8Y 2X8Z 2X90 2X92 2X93 2X94 2X95 2X96 2X97
Related PRD ID	PRD_000560
Descriptor	ANGIOTENSIN CONVERTING ENZYME, beta-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, [N2-[(S)-1-CARBOXY-3-PHENYLPROPYL]-L-LYSYL-L-PROLINE, ... (7 entities in total)
Functional Keywords	hydrolase, ace inhibitor, zinc metallopeptidase
Biological source	DROSOPHILA MELANOGASTER (FRUIT FLY)
Total number of polymer chains	1
Total formula weight	71853.79
Authors	Akif, M.,Georgiadis, D.,Mahajan, A.,Dive, V.,Sturrock, E.D.,Isaac, R.E.,Acharya, K.R. (deposition date: 2010-03-14, release date: 2010-06-02, Last modification date: 2020-07-29)
Primary citation	Akif, M.,Georgiadis, D.,Mahajan, A.,Dive, V.,Sturrock, E.D.,Isaac, R.E.,Acharya, K.R. High Resolution Crystal Structures of Drosophila Melanogaster Angiotensin Converting Enzyme in Complex with Novel Inhibitors and Anti- Hypertensive Drugs. J.Mol.Biol., 400:502-, 2010 Cited by PubMed: 20488190 DOI: 10.1016/J.JMB.2010.05.024 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.98 Å)

Structure validation