2WOQ
Porphobilinogen Synthase (HemB) in Complex with 5-acetamido-4- oxohexanoic acid (Alaremycin 2)
Summary for 2WOQ
Entry DOI | 10.2210/pdb2woq/pdb |
Related | 1B4K 1GZG 1W54 1W56 1W5M 1W5N 1W5O 1W5P 1W5Q 2C13 2C14 2C15 2C16 2C18 2C19 |
Descriptor | DELTA-AMINOLEVULINIC ACID DEHYDRATASE, ALAREMYCIN 2, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | lyase-antibiotic complex, lyase antibiotic complex, metal-binding, heme biosynthesis, porphyrin biosynthesis, porpobilinogen synthase, hemb, lyase, inhibitor, lyase/antibiotic |
Biological source | PSEUDOMONAS AERUGINOSA |
Total number of polymer chains | 1 |
Total formula weight | 39432.90 |
Authors | Heinemann, I.U.,Schulz, C.,Schubert, W.-D.,Heinz, D.W.,Wang, Y.-G.,Kobayashi, Y.,Awa, Y.,Wachi, M.,Jahn, D.,Jahn, M. (deposition date: 2009-07-27, release date: 2009-10-27, Last modification date: 2023-12-20) |
Primary citation | Heinemann, I.U.,Schulz, C.,Schubert, W.D.,Heinz, D.W.,Wang, Y.G.,Kobayashi, Y.,Awa, Y.,Wachi, M.,Jahn, D.,Jahn, M. Structure of the heme biosynthetic Pseudomonas aeruginosa porphobilinogen synthase in complex with the antibiotic alaremycin. Antimicrob. Agents Chemother., 54:267-272, 2010 Cited by PubMed: 19822707DOI: 10.1128/AAC.00553-09 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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