1W5O
Stepwise introduction of zinc binding site into porphobilinogen synthase of Pseudomonas aeruginosa (mutations A129C, D131C and D139C)
Summary for 1W5O
| Entry DOI | 10.2210/pdb1w5o/pdb |
| Related | 1B4K 1GZG 1W54 1W56 1W5M 1W5N 1W5P 1W5Q |
| Descriptor | DELTA-AMINOLEVULINIC ACID DEHYDRATASE, GLYCEROL, POTASSIUM ION, ... (6 entities in total) |
| Functional Keywords | synthase, evolution, metalloenzyme, porphobilinogen synthase, pseudomonas aeruginosa, protein engineering |
| Biological source | PSEUDOMONAS AERUGINOSA |
| Total number of polymer chains | 2 |
| Total formula weight | 74585.96 |
| Authors | Frere, F.,Reents, H.,Schubert, W.-D.,Heinz, D.W.,Jahn, D. (deposition date: 2004-08-09, release date: 2005-01-19, Last modification date: 2023-12-13) |
| Primary citation | Frere, F.,Reents, H.,Schubert, W.-D.,Heinz, D.W.,Jahn, D. Tracking the Evolution of Porphobilinogen Synthase Metal Dependence in Vitro J.Mol.Biol., 345:1059-, 2005 Cited by PubMed: 15644204DOI: 10.1016/J.JMB.2004.10.053 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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