2VFA
Crystal structure of a chimera of Plasmodium falciparum and human hypoxanthine-guanine phosphoribosyl transferases
Summary for 2VFA
Entry DOI | 10.2210/pdb2vfa/pdb |
Related | 1BZY 1CJB 1D6N 1HMP 1Z7G |
Descriptor | HYPOXANTHINE-GUANINE-XANTHINE PHOSPHORIBOSYLTRANSFERASE, HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE, GUANOSINE-5'-MONOPHOSPHATE, SULFATE ION, ... (4 entities in total) |
Functional Keywords | hypoxanthine-guanine phosphoribosyl transferase (hgprt), purine salvage, disease mutation, glycosyltransferase, transferase, metal-binding, gout, chimera, magnesium |
Biological source | PLASMODIUM FALCIPARUM More |
Cellular location | Cytoplasm: P20035 |
Total number of polymer chains | 2 |
Total formula weight | 52584.45 |
Authors | Gayathri, P.,Selvi, T.S.,Subbayya, I.N.S.,Ashok, C.S.,Balaram, H.,Murthy, M.R.N. (deposition date: 2007-11-02, release date: 2008-06-17, Last modification date: 2023-12-13) |
Primary citation | Gayathri, P.,Sujay Subbayya, I.N.,Ashok, C.S.,Selvi, T.S.,Balaram, H.,Murthy, M.R.N. Crystal Structure of a Chimera of Human and Plasmodium Falciparum Hypoxanthine Guanine Phosphoribosyltransferases Provides Insights Into Oligomerization. Proteins, 73:1010-, 2008 Cited by PubMed: 18536021DOI: 10.1002/PROT.22129 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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